POLYMER-BOUND TRIPHENYLPHOSPHINE AS TRACELESS REAGENT FOR MITSUNOBU REACTIONS IN COMBINATORIAL CHEMISTRY - SYNTHESIS OF ARYL ETHERS FROM PHENOLS AND ALCOHOLS

Authors
TUNOORI AR DUTTA D GEORG GI
Citation
Ar. Tunoori et al., POLYMER-BOUND TRIPHENYLPHOSPHINE AS TRACELESS REAGENT FOR MITSUNOBU REACTIONS IN COMBINATORIAL CHEMISTRY - SYNTHESIS OF ARYL ETHERS FROM PHENOLS AND ALCOHOLS, Tetrahedron letters, 39(48), 1998, pp. 8751-8754
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
48
Year of publication
1998
Pages
8751 - 8754
Database
ISI
SICI code
0040-4039(1998)39:48<8751:PTATRF>2.0.ZU;2-1
Abstract
The synthesis of aryl ethers from phenols and alcohols using polymer-b ound triphenylphosphine and diethyl azodicarboxylate (DEAD) is describ ed. The polymer-bound triphenylphosphines are easily removed by filtra tion from the reaction products. This method is operationally simple a nd provides the products with high purity and in good yields. (C) 1998 Elsevier Science Ltd. All rights reserved.