Y. Baba et al., HYPERINTENSE BASAL GANGLIA LESIONS ON T1-WEIGHTED IMAGES IN HEREDITARY HEMORRHAGIC TELANGIECTASIA WITH HEPATIC INVOLVEMENT, Journal of computer assisted tomography, 22(6), 1998, pp. 976-979
We present two patients with hereditary hemorrhagic telangiectasia (HH
T) accompanied by multiple hepatic arteriovenous malformations (AVMs)
whose cranial MRI: demonstrated high signal intensity in the basal gan
glia on T1-weighted images. Manganese levels in peripheral blood were
very high in both patients. These two cases indicate that there may be
a significant relationship between high intensity basal ganglia and m
ultiple hepatic AVMs. While the precise mechanism of the signal altern
ation in the basal ganglia is unproven, high blood levels of manganese
in these patients suggest that abnormal intensity in the basal gangli
a may be due to deposition of manganese.