HYPERINTENSE BASAL GANGLIA LESIONS ON T1-WEIGHTED IMAGES IN HEREDITARY HEMORRHAGIC TELANGIECTASIA WITH HEPATIC INVOLVEMENT

Citation
Y. Baba et al., HYPERINTENSE BASAL GANGLIA LESIONS ON T1-WEIGHTED IMAGES IN HEREDITARY HEMORRHAGIC TELANGIECTASIA WITH HEPATIC INVOLVEMENT, Journal of computer assisted tomography, 22(6), 1998, pp. 976-979
Citations number
19
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
ISSN journal
03638715
Volume
22
Issue
6
Year of publication
1998
Pages
976 - 979
Database
ISI
SICI code
0363-8715(1998)22:6<976:HBGLOT>2.0.ZU;2-L
Abstract
We present two patients with hereditary hemorrhagic telangiectasia (HH T) accompanied by multiple hepatic arteriovenous malformations (AVMs) whose cranial MRI: demonstrated high signal intensity in the basal gan glia on T1-weighted images. Manganese levels in peripheral blood were very high in both patients. These two cases indicate that there may be a significant relationship between high intensity basal ganglia and m ultiple hepatic AVMs. While the precise mechanism of the signal altern ation in the basal ganglia is unproven, high blood levels of manganese in these patients suggest that abnormal intensity in the basal gangli a may be due to deposition of manganese.