Statistical Challenges in Biological Networks

Citation
George Michailidis, Statistical Challenges in Biological Networks, Journal of computational and graphical statistics , 21(4), 2012, pp. 840-855
ISSN journal
10618600
Volume
21
Issue
4
Year of publication
2012
Pages
840 - 855
Database
ACNP
SICI code
Abstract
Advances in high-throughput technologies have made available a large amount of genomic, transcriptomic, proteomic, and metabolomic biological data. For biomedical researchers to make sense of the vast amount of information contained in such data, and incorporate structural information and knowledge gleaned from targeted experiments, networks can play a key role in their understanding of biological processes and mechanisms. This article discusses some topics pertaining to biological networks and outline the role of statistical methods in their analysis.