L. Odum et Hw. Nielsen, BIKUNIN AND ALPHA(1)-MICROGLOBULIN IN HUMAN ZONA-PELLUCIDA AND CONNECTIVE-TISSUE, Histochemical Journal, 29(3), 1997, pp. 199-203
The occurrence of bikunin and alpha(1)-microglobulin was investigated
in human ovary and Fallopian tubes. Bikunin and al microglobulin are t
ranscribed in the liver from a common gene. Bikunin immunoreactivity w
as detected in the zona pellucida. A positive reaction for bikunin was
also observed in connective tissue of the oviduct. In addition, mast
cells showed a more intense positive reaction than the surrounding con
nective tissue. Specific displaceable alpha(1)-microglobulin immunorea
ctivity was revealed in the zona pellucida. The data suggest that biku
nin and al-microglobulin are trapped in the zona pellucida.