Cf. Sharpley, PSYCHOSOCIAL STRESS-INDUCED HEART-RATE REACTIVITY AND ATHEROGENESIS -CAUSE OR CORRELATION, Journal of behavioral medicine, 21(5), 1998, pp. 411-432
The relationship between heart rate reactivity and atherogenesis is ex
amined Data from empirical studies are presented which support theoret
ical suggestions that it is the heart rate itself rather than the incr
ease in heart rate following the onset of a stressor which is causally
related to the development of arterial atherosclerosis. Several direc
tions for research which will clarify this issue are discussed, with r
ecent developments in the detection of atherosclerosis suggested as fo
rming the basis of more reliable investigation of the effects of cardi
ac output variables upon arterial atherogenesis.