S. Bejerot et O. Bodlund, RESPONSE TO HIGH-DOSES OF CITALOPRAM IN TREATMENT-RESISTANT OBSESSIVE-COMPULSIVE DISORDER, Acta psychiatrica Scandinavica, 98(5), 1998, pp. 423-424
We report a severe case of obsessive-compulsive disorder (OCD) that re
sponded to very high doses of citalopram (160 mg/day) after a poor res
ponse to clomipramine 250 mg/day for several years, alone or in combin
ation with buspirone 30 mg/day or flupenthixol 4 mg/day. The patient h
ad previously been submitted for capsulotomy which was declined, proba
bly due to the magical content of her obsessions, which resembled delu
sions.