PULLULANASE - MODEL PROTEIN SUBSTRATE FOR THE GENERAL SECRETORY PATHWAY OF GRAM-NEGATIVE BACTERIA

Authors
PUGSLEY AP FRANCETIC O HARDIE K POSSOT OM SAUVONNET N SEYDEL A
Citation
Ap. Pugsley et al., PULLULANASE - MODEL PROTEIN SUBSTRATE FOR THE GENERAL SECRETORY PATHWAY OF GRAM-NEGATIVE BACTERIA, Folia microbiologica, 42(3), 1997, pp. 184-192
Citations number
58
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Folia microbiologica → ACNP
ISSN journal
00155632
Volume
42
Issue
3
Year of publication
1997
Pages
184 - 192
Database
ISI
SICI code
0015-5632(1997)42:3<184:P-MPSF>2.0.ZU;2-H
Abstract
Pullulanase of Klebsiella oxytoca is one of a wide variety of extracel lular proteins that are secreted by Gram-negative bacteria by the comp lex main terminal branch (MTB) of the general secretory pathway. The r oles of some of the 14 components of the MTB are now becoming clear. I n this review it is proposed that most of these proteins form a comple x, the secreton, that spans the cell envelope to control the opening a nd closing of channel in the outer membrane. Progress toward the goal of testing this model is reviewed.