STRUCTURE-REACTIVITY RELATIONSHIPS IN THE RATE OF ESTERIFICATION BY ACETYLIMIDAZOLE - THE INFLUENCE OF THE 2ND HYDROXY GROUP AND OF THE LENGTH OF THE N-OMEGA-HYDROXY-N-ALKYL CHAIN IN 3-(N-METHYL, EGA-HYDROXY-N-ALKYL)AMINO-2-TERT-BUTYLPROPAN-1-OLS

Authors
MADDER A DECLERCQ PJ MASKILL H
Citation
A. Madder et al., STRUCTURE-REACTIVITY RELATIONSHIPS IN THE RATE OF ESTERIFICATION BY ACETYLIMIDAZOLE - THE INFLUENCE OF THE 2ND HYDROXY GROUP AND OF THE LENGTH OF THE N-OMEGA-HYDROXY-N-ALKYL CHAIN IN 3-(N-METHYL, EGA-HYDROXY-N-ALKYL)AMINO-2-TERT-BUTYLPROPAN-1-OLS, Perkin transactions. 2, (5), 1997, pp. 851-852
Citations number
18
Categorie Soggetti
Chemistry Physical","Chemistry Inorganic & Nuclear
Journal title
Perkin transactions. 2 → ACNP
ISSN journal
03009580
Issue
5
Year of publication
1997
Pages
851 - 852
Database
ISI
SICI code
0300-9580(1997):5<851:SRITRO>2.0.ZU;2-7
Abstract
Enforced intramolecular hydrogen bonding facilitates intramolecular ge neral base catalysis in the acetylation of a family of alpha,omega-ami no alcohols by acetylimidazole, and the site of acetylation when there are two hydroxy groups is determined by the relative ease of intramol ecular hydrogen bonding rather than by intermolecular steric effects.