EXTRACTIVE BIOCATALYSIS - A POWERFUL TOOL IN SELECTIVITY CONTROL IN YEAST BIOTRANSFORMATIONS

Authors
DARRIGO P FUGANTI C FANTONI GP SERVI S
Citation
P. Darrigo et al., EXTRACTIVE BIOCATALYSIS - A POWERFUL TOOL IN SELECTIVITY CONTROL IN YEAST BIOTRANSFORMATIONS, Tetrahedron, 54(49), 1998, pp. 15017-15026
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
49
Year of publication
1998
Pages
15017 - 15026
Database
ISI
SICI code
0040-4020(1998)54:49<15017:EB-APT>2.0.ZU;2-7
Abstract
The effect of absorbing resins on the yeast reduction of cl,P-unsatura ted carbonyl compounds is reported. Enantioselectivity, chemoselectivi ty and space-time yields of the biotransformation are impressively enh anced. The distribution of substrates and products between the resin a nd the water phase shows that the improved selectivity has to be attri buted to the control of substrate concentration, (C) 1998 Elsevier Sci ence Ltd. All rights reserved.