HIBISPEPTIN-B, A NOVEL CYCLIC PEPTIDE FROM HIBISCUS-SYRIACUS

Citation
Bs. Yun et al., HIBISPEPTIN-B, A NOVEL CYCLIC PEPTIDE FROM HIBISCUS-SYRIACUS, Tetrahedron, 54(50), 1998, pp. 15155-15160
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404020
Volume
54
Issue
50
Year of publication
1998
Pages
15155 - 15160
Database
ISI
SICI code
0040-4020(1998)54:50<15155:HANCPF>2.0.ZU;2-E
Abstract
A new cyclic peptide, designated as hibispeptin B, has been isolated f rom the root bark of Hibiscus syriacus. Hibispeptin B has a unique ami no acid unit assigned as 2-amino-3-(2-hydroxy-5-aminoacetylbenzyl)pent anoic acid (Ahabpa) in cyclic core. Its structure was established as c yclo[Ahabpa(-pyro-Glu)-Pro-Leu-Leu-] on the basis of various spectrosc opic analyses. Configurations of all normal amino acids were determine d as L by chiral-TLC analysis. (C) 1998 Elsevier Science Ltd. All; rig hts reserved.