2,5-DIMETHYLPYRROLE PROTECTION FACILITATES COPPER(I)-MEDIATED METHOXYLATIONS OF ARYL IODIDES IN THE PRESENCE OF ANILINES

Authors
RAGAN JA MAKOWSKI TW CASTALDI MJ HILL PD
Citation
Ja. Ragan et al., 2,5-DIMETHYLPYRROLE PROTECTION FACILITATES COPPER(I)-MEDIATED METHOXYLATIONS OF ARYL IODIDES IN THE PRESENCE OF ANILINES, Synthesis, (11), 1998, pp. 1599-1603
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
11
Year of publication
1998
Pages
1599 - 1603
Database
ISI
SICI code
0039-7881(1998):11<1599:2PFCM>2.0.ZU;2-5
Abstract
Converting iodoanilines to the corresponding 2,5-dimethylpyrroles was found to facilitate CuCl-mediated methoxide substitution. Examples wit h ortho-, meta-, or para-relationships between the iodide and aniline are presented. Several other aniline blocking groups were investigated and found not to be successful in this sequence.