HUMAN SPERM MOTILITY AND LIPID-PEROXIDATION IN DIFFERENT ASCORBIC-ACID CONCENTRATIONS - AN IN-VITRO ANALYSIS

Authors
Citation
A. Verma et Kc. Kanwar, HUMAN SPERM MOTILITY AND LIPID-PEROXIDATION IN DIFFERENT ASCORBIC-ACID CONCENTRATIONS - AN IN-VITRO ANALYSIS, Andrologia, 30(6), 1998, pp. 325-329
Citations number
34
Categorie Soggetti
Andrology
Journal title
ISSN journal
03034569
Volume
30
Issue
6
Year of publication
1998
Pages
325 - 329
Database
ISI
SICI code
0303-4569(1998)30:6<325:HSMALI>2.0.ZU;2-I
Abstract
Human spermatozoal motility, viability and lipid peroxidation (LPO) ha ve been assessed in Ringer-Tyrode supplemented with different concentr ations of ascorbic acid (AA) ranging from 50 to 4000 mu M. Ascorbic ac id in concentrations below 1000 mu M protects spermatozoa from free ra dical damage as evidenced from improvement in their motility and viabi lity. Concomitantly, there is also witnessed depletion of malondialdeh yde generation tan end product of LPO) following AA treatment. Ascorbi c acid at 1000 mu M concentration and above, however, is not protectiv e, as evidenced by abrupt fall in sperm motility and viability and con comitant increase in LPO.