SYNTHETIC STUDIES TOWARD POTENT CYTOTOXIC AGENTS AMPHIDINOLIDES - SYNTHESIS OF THE C-1-C-18 MOIETY OF AMPHIDINOLIDE-G, AMPHIDINOLIDE-H AND AMPHIDINOLIDE-L

Citation
Tk. Chakraborty et Vr. Suresh, SYNTHETIC STUDIES TOWARD POTENT CYTOTOXIC AGENTS AMPHIDINOLIDES - SYNTHESIS OF THE C-1-C-18 MOIETY OF AMPHIDINOLIDE-G, AMPHIDINOLIDE-H AND AMPHIDINOLIDE-L, Tetrahedron letters, 39(49), 1998, pp. 9109-9112
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
39
Issue
49
Year of publication
1998
Pages
9109 - 9112
Database
ISI
SICI code
0040-4039(1998)39:49<9109:SSTPCA>2.0.ZU;2-V
Abstract
Stereoselective synthesis of the (8S, 9S, 11R, 16S)-C-1-C-18 Segment 1 of amphidinolides G, H and L, bearing the unique trisubstituted ''s-c is-1,3-diene'' moiety (C-28(29)=C-13-C-14=C-15), has been achieved for the first time following a highly efficient convergent strategy. (C) 1998 Elsevier Science Ltd. All rights reserved.