DIAGNOSTIC QUALITY IN HYSTEROSALPINGOGRAPHY - COMPARISON BETWEEN IODIXANOL AND IOTROLAN

Purpose: To compare the diagnostic quality and adverse events of the w ater-soluble, non-ionic, iso-osmolar, dimeric contrast media iodixanol and iotrolan in hysterosalpingography (HSG). Material and Methods. On e hundred and twenty patients participated in a double-blind randomize d parallel-group phase-III study. Questionnaires and patient interview s were used. Diagnostic quality was assessed using a visual analogue s cale and the quality in specific regions was rated using a categorical scale. Results. Overall diagnostic quality was equal for the two grou ps. There was no statistically significant difference between the two groups in diagnostic quality in the specific regions of interest. No d ifferences between the contrast media were found with regard to advers e events. Conclusion. Both contrast media provided images of high diag nostic quality in HSG.