Several studies have underlined the high prevalence of psychiatric sym
ptoms and disorders in thyroid diseases. The aim of this study was to
evaluate the prevalence of psychiatric disorders in 93 inpatients affe
cted by different thyroid diseases during their lifetimes, by means of
a standardized instrument, i.e., the Structured Clinical Interview fo
r Diagnostic and Statistical Manual of Mental Disorders-III-Revised, U
pjohn Version (SCID-UP-R). The results showed higher rates of panic di
sorder, simple phobia, obsessive-compulsive disorder, major depressive
disorder, bipolar disorder and cyclothymia in thyroid patients than i
n the general population. These findings would suggest that the co-occ
urrence of psychiatric and thyroid diseases may be the result of commo
n biochemical abnormalities.