Selected studies are summarized that measure interfragmentary fracture
displacements in 6 degrees of freedom at intervals throughout healing
in groups of patients with tibial diaphyseal fractures treated by ext
ernal skeletal fixation. The results are compared,vith those obtained
from experimental studies in which the ideal mechanical conditions for
fracture healing were predicted. A finite element analysis model of t
he healing tibial fracture also was developed. Measured data were used
for the analysis, and stress and strain patterns were defined for dif
ferent stages of healing. Interfragmentary movement measured in the fi
rst 6 weeks after injury usually is a magnitude smaller in patients tr
eated by external fixation than in patients treated with cast immobili
zation. This movement can be much smaller than that predicted to be op
timal by experimental studies. A greater amplitude can be achieved, ev
en in stable fractures, by ensuring patient activity. The interfragmen
tary movement is elastic during loading activity and is generally sinu
soidal during steady walking. At the time of dynamization (the unlocki
ng of the frame), a permanent set occurs at the fracture site in all p
lanes, The cyclical movement range in each plane often decreases immed
iately after unlocking. The model analysis study of fracture healing p
redicts that tissue damage may occur in the later (hard callus) phase
of healing, even while the fixation device is in place, because of abn
ormally high stresses and strains. This study indicates that fracture
mechanics should be controlled more rigorously to provide amplitudes o
f movement in the first 4 to 6 weeks after fracture. The rigidity of f
ixation should be increased in the subsequent weeks until the fracture
has healed and the frame is removed.