A RANDOMIZED STUDY COMPARING LEVONORGESTREL INTRAUTERINE SYSTEM (LNG IUS) AND TRANSCERVICAL RESECTION OF THE ENDOMETRIUM (TCRE) IN THE TREATMENT OF MENORRHAGIA - PRELIMINARY-RESULTS
N. Kittelsen et O. Istre, A RANDOMIZED STUDY COMPARING LEVONORGESTREL INTRAUTERINE SYSTEM (LNG IUS) AND TRANSCERVICAL RESECTION OF THE ENDOMETRIUM (TCRE) IN THE TREATMENT OF MENORRHAGIA - PRELIMINARY-RESULTS, Gynaecological endoscopy, 7(2), 1998, pp. 61-65
Objective To identify the effect of the levonorgestrel coil (Mirena; L
NG IUS) vs, transcervical resection of the endometrium (TCRE) for trea
tment of menorrhagia. Design A randomized study of 60 patients perform
ed at a gynaecological clinic specializing in operative hysteroscopy.
Results 24 patients in the LNG IUS group and 29 patients in the TCRE g
roup completed 20 months of follow up. In the TCRE group one patient r
efused to continue after the result of randomization. Reasons for disc
ontinuation in the LNG IUS group included abdominal pain (2), acne (1)
and bleeding or continuous spotting (3). The bleeding intensity was a
ssessed using the PBAC score and was reduced in both groups, from 418
to 42 in the LNG IUS group, and from 378 to 6.6 in the TCRE group. Con
clusion Both methods have a dramatic effect on bleeding intensity and
furthermore the LNG IUS is reversible and has no operative hazards or
side-effects.