Objective. To report 12 cases of chondrosarcoma in a rare location, th
e short tubular bones of the hands and feet, as well as 12 cases of en
chondroma in similar locations, emphasizing the radiologic and histopa
thologic features. Design and patients. All relevant cases that had bo
th histologic slides and radiographs available were taken from the fil
es of one orthopedic referral hospital and the personal files of one o
f the authors. A similar number of enchondroma cases was selected at r
andom from the files. Results and conclusions. One malignancy arose in
a background of enchondromatosis, with all the others being solitary
lesions. A pathologic diagnosis of malignancy is often difficult in th
e absence of radiologic signs of malignancy (cortical destruction with
or without soft tissue extension). However, three cases were unusual
in that the initial radiograph demonstrated a benign appearance. Anoth
er group of three malignancies was surprisingly indolent biologically.
The treatment of choice is ray resection (or more limited amputation
in a lesion of the middle or distal phalanx).