FAILURE OF SORIVUDINE THERAPY IN PROGRESSIVE OUTER RETINAL NECROSIS CAUSED BY VARICELLA-ZOSTER VIRUS

Authors
ROSENTHAL G BARTZSCHMIDT K WALTER P KIRCHHOF B HEIMANN K
Citation
G. Rosenthal et al., FAILURE OF SORIVUDINE THERAPY IN PROGRESSIVE OUTER RETINAL NECROSIS CAUSED BY VARICELLA-ZOSTER VIRUS, Australian and New Zealand journal of ophthamology (Print), 26(4), 1998, pp. 327-328
Citations number
2
Categorie Soggetti
Ophthalmology
Journal title
Australian and New Zealand journal of ophthamology (Print) → ACNP
ISSN journal
08149763
Volume
26
Issue
4
Year of publication
1998
Pages
327 - 328
Database
ISI
SICI code
0814-9763(1998)26:4<327:FOSTIP>2.0.ZU;2-T
Abstract
Background: We report on the case of a 23-year-old female who presente d with ocular signs of progressive outer retinal necrosis (PORN) syndr ome and who failed to respond to acyclovir; ganciclovir; foscarnet and oral sorivudine. Methods: The patient was treated with the antiviral drugs acyclovir, ganciclovir, foscarnet and oral sorivudine. Results: The patient failed to respond to a combination of antiviral drugs. Unf ortunately, progression of the retinitis occurred, which led to blindn ess. Conclusion: Despite new drugs. the prognosis of PORN is poor and recurrence is common.