Objective: It has long been thought that anger is important in the dev
elopment of essential hypertension. However, tests of this hypothesis
have yielded conflicting findings. This study prospectively examined t
he relationship between anger expression style and incident hypertensi
on in a population sample of middle-aged men. Methods: Participants we
re 537 initially normotensive men from eastern Finland, who completed
a medical examination and series of psychological questionnaires at ba
seline and at 4-year follow-up. Anger expression was assessed by Spiel
berger's Anger-out and Anger-in scales. Results: At follow-up, 104 men
(19.4%) were hypertensive (blood pressure greater than or equal to 16
5 mm Hg systolic and/or 95 mm Hg diastolic). Age adjusted logistic reg
ression analyses revealed that each 1-point increase in Anger-out was
associated with a 12% increase in risk of hypertension after 4 years o
f follow-up (p < .002), which corresponded to a two-fold increased ris
k of hypertension among men with scores in the top tertile of the Ange
r-out scale, relative to those with scores in the bottom tertile (odds
ratio = 2.00, 95% confidence interval 1.20-3.38). Each 1-point increa
se on the Anger-in scale also was related to a 12% increased risk of h
ypertension (p < .01). Adjustments for body mass index, smoking, alcoh
ol consumption, physical activity, a positive parental history of hype
rtension, and baseline resting diastolic blood pressure had Little imp
act on the findings. Conclusions: These data provide strong epidemiolo
gical evidence for a positive relationship between anger expression st
yle and subsequent hypertension, independent of known risk factors. Fi
ndings support the hypothesis that extreme expression of anger in eith
er direction has adverse cardiovascular consequences.