COMPARISON OF THE ANALGESIC EFFECT OF EMLA(R) CREAM AND EMLA(R) PATCHON NORMAL SKIN EVALUATED WITH LASER-INDUCED PAIN STIMULI

Authors
EGEKVIST H BJERRING P
Citation
H. Egekvist et P. Bjerring, COMPARISON OF THE ANALGESIC EFFECT OF EMLA(R) CREAM AND EMLA(R) PATCHON NORMAL SKIN EVALUATED WITH LASER-INDUCED PAIN STIMULI, Acta dermato-venereologica, 77(3), 1997, pp. 214-216
Citations number
11
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Acta dermato-venereologica → ACNP
ISSN journal
00015555
Volume
77
Issue
3
Year of publication
1997
Pages
214 - 216
Database
ISI
SICI code
0001-5555(1997)77:3<214:COTAEO>2.0.ZU;2-S
Abstract
In the present study the onset, duration and efficacy of the analgesic effect of EMLA(R) patch compared to EMLA(R) cream were investigated o n the skin of the forearms of 12 healthy adults, EMLA(R) patch and cre am were applied for 30, 60 and 120 min, The pain threshold was determi ned 5 min after removal of the test substance, using high-energy argon laser stimuli, and thereafter every 30 min for 4 h, After 120 min of application, both EMLA(R) cream and EMLA(R) patch ensured total analge sia, The clinical analgesic efficacy of EMLA(R) patch was found equal to that of EMLA(R) cream.