The effect of apolipoprotein E genotypes on the occurrence of HIV deme
ntia and HIV encephalitis was studied in a sample of 132 AIDS patients
in whom clinical data on dementia was available and full autopsy had
been performed. There was no statistically significant correlation bet
ween risk of HIV dementia or HIV encephalitis in relation to apolipopr
otein E genotypes, even after correction for length of survival with A
IDS and antiretroviral treatment.