GENOTYPING FOR POLYMORPHISMS IN INTERFERON-GAMMA, INTERLEUKIN-10, TRANSFORMING GROWTH-FACTOR-BETA-1 AND TUMOR-NECROSIS-FACTOR-ALPHA GENES -A TECHNICAL REPORT

Citation
C. Perrey et al., GENOTYPING FOR POLYMORPHISMS IN INTERFERON-GAMMA, INTERLEUKIN-10, TRANSFORMING GROWTH-FACTOR-BETA-1 AND TUMOR-NECROSIS-FACTOR-ALPHA GENES -A TECHNICAL REPORT, Transplant immunology, 6(3), 1998, pp. 193-197
Citations number
13
Categorie Soggetti
Transplantation,Immunology
Journal title
ISSN journal
09663274
Volume
6
Issue
3
Year of publication
1998
Pages
193 - 197
Database
ISI
SICI code
0966-3274(1998)6:3<193:GFPIII>2.0.ZU;2-3
Abstract
Polymorphic Variants of cytokine genes are associated with acute and c hronic transplant rejection. In this technical report, the methods cur rently used in our centre to genotype individuals for interferon-gamma , interleukin-10, transforming growth factor-beta 1 and tumour necrosi s factor-alpha are described in detail. The DNA sequences of primers a nd probes, and conditions for polymerase chain reactions are given, an d the allele and genotype frequencies in our control populations are s ummarized.