INFLUENCE OF ESTER CHAIN-LENGTH ON LIPASE-CATALYZED HYDROLYZES OF MESO-OXIRANEDIMETHANOL ESTERS

Authors
MOSELEY JD STAUNTON J
Citation
Jd. Moseley et J. Staunton, INFLUENCE OF ESTER CHAIN-LENGTH ON LIPASE-CATALYZED HYDROLYZES OF MESO-OXIRANEDIMETHANOL ESTERS, Tetrahedron : asymmetry, 9(20), 1998, pp. 3619-3623
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
20
Year of publication
1998
Pages
3619 - 3623
Database
ISI
SICI code
0957-4166(1998)9:20<3619:IOECOL>2.0.ZU;2-O
Abstract
A range of meso-oxiranedimethanol diesters have been hydrolysed by a s election of microbial and porcine derived lipases. The results reveal the effects of eater substitution, particularly chain length, on the h ydrolyses. General conclusions are made which demonstrate that ester c hain length can be 'tuned' to achieve optimum enantiomeric enrichment for a given substrate. (C) 1998 Elsevier Science Ltd. All rights reser ved.