Gj. Hademenos et al., ANATOMICAL AND MORPHOLOGICAL FACTORS CORRELATING WITH RUPTURE OF INTRACRANIAL ANEURYSMS IN PATIENTS REFERRED FOR ENDOVASCULAR TREATMENT, Neuroradiology, 40(11), 1998, pp. 755-760
Citations number
48
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging","Clinical Neurology
The size of intracranial aneurysms is the only characteristic shown to
correlate with their rupture. However, the critical size for rupture
has varied considerably among previous accounts and remains a point of
controversy. Our goal was to identify statistically significant clini
cal and morphological factors predictive of the occurrence of rupture
and aneurysm size in patients referred for endovascular treatment. We
retrospectively recorded the following factors from 74 patients who pr
esented with ruptured (40) or unruptured (34) aneurysms: aneurysm morp
hology (uni/multilobulated), location (anterior/posterior), maximum di
ameter, diameter of the neck, and the patient's age and sex. We perfor
med stepwise discriminant, and stepwise and logistic regression analys
is to identify factors predicting rupture and the size of the aneurysm
at rupture. The mean diameter of the ruptured aneurysms was 11.9 +/-
6.3 mm, range 3.0-33.0 mm, and that of the unruptured aneurysm 13.5 +/
- 5.8 mm, range 5.0-30 mm. Stepwise discriminant analysis identified a
neurysm morphology (P < 0.001) and location in the intracranial circul
ation (P < 0.001) as statistically significant factors in predicting r
upture. Stepwise regression analysis revealed that aneurysm morphology
and the size of the neck were predictors of aneurysm size at rupture.