PHEOCHROMOCYTOMA - CURRENT DIAGNOSTIC METHODS

Citation
Lm. Dourthe et al., PHEOCHROMOCYTOMA - CURRENT DIAGNOSTIC METHODS, La Semaine des hopitaux de Paris, 74(33-34), 1998, pp. 1263-1268
Citations number
23
Categorie Soggetti
Medicine, General & Internal
ISSN journal
00371777
Volume
74
Issue
33-34
Year of publication
1998
Pages
1263 - 1268
Database
ISI
SICI code
0037-1777(1998)74:33-34<1263:P-CDM>2.0.ZU;2-D
Abstract
Pheochromocytoma is an uncommon tumor usually derived from the adrenal medulla. Headache, excessive sweating, tachycardia, and arterial hype rtension are the typical symptoms. Atypical presentations are common. The diagnosis relies on demonstration of elevated plasma levels of met hoxamines, best achieved by high performance liquid chromatography. Th e tumor can be identified by computed tomography A scintiscan after ad ministration of MIBG is useful to look for multiple foci or evidence o f malignancy. Multiple endocrine neoplasia should be looked for. The t umor should be removed surgically. Preoperative management is essentia l to avoid paroxysmal hypertension or cardiovascular collapse during m obilization of the tumor. The prognosis is good, although some patient s remain hypertensive.