MALIGNANT INSULINOMA PRESENTING A NONFUNCTIONING METASTATIC LIVER-TUMOR 14 YEARS AFTER RESECTION OF THE PRIMARY TUMOR

A 58-year-old woman who had undergone resection of insulinoma 14 year earlier visited our clinic complaining of abdominal discomfort. Comput erized tomographic scan showed multiple liver tumors, and a diagnosis of metastatic tumor of malignant islet cell tumor was confirmed histol ogically. No oversecretion of hormones or hypoglycemic episode was obs erved on readmission. Thus, the insulinoma seemed to have transformed to a clinically non-functioning tumor. The patient was treated with tr anscatheter arterial embolization, resulting in clinical improvement w ith marked reduction in tumor size. Features of interest in this case included; (1) transformation to nonfunctioning metastatic liver tumor 14 years after resection of insulinoma, (2) the usefulness of transcat heter arterial embolization for multiple metastatic tumor of malignant islet cell tumor.