Many factors influence the extent and rate at which enamel wears. Clin
ical studies in humans are limited by difficulties in the accurate qua
ntification of intra-oral wear and by a lack of control over the oral
environment. The purpose of this study was to determine the wear chara
cteristics of human dental enamel under controlled experimental condit
ions. An electro-mechanical tooth wear machine, in which opposing enam
el surfaces of sectioned, extracted teeth were worn under various cond
itions, was used to simulate tooth grinding or bruxism. Enamel surface
wear was quantified by weight to an accuracy of 0.1 mg, with water up
take and loss controlled. The variables considered included the struct
ure and hardness of enamel, facet area, duration of tooth contact, rel
ative speed of opposing surfaces, temperature, load, pH, and the natur
e of the lubricant. Enamel wear under non-lubricated conditions increa
sed with increasing load over the range of 1.7 to 16.2 kg. The additio
n of a liquid lubricant (pH = 7) reduced enamel wear up to 6.7 kg, but
when the load increased above this threshold, the rate of wear increa
sed dramatically. With the viscosity of the lubricant constant and pH
= 3, the rate of wear was further reduced to less than 10% of the non-
lubricated rate at 9.95 kg, after which the rate again increased subst
antially. Under more extreme conditions (pH = 1.2, simulating gastric
acids), the wear was excessive under all experimental loads. When sali
va was used as a lubricant, the amount of wear was relatively low at 9
.95 kg, but rapid wear occurred at 14.2 kg and above. These results in
dicate that under non-lubricated conditions, enamel wear remains low a
t high loads due to the dry lubricating capabilities of fine enamel po
wder. Under lubricated conditions, low loads with an acidic lubricant
lead to little enamel wear, whereas very low pH results in a high rate
of wear under all loads.