(-CAMPHOR-DERIVED TRIDENTATE AND TETRADENTATE AMINO-ALCOHOLS - SYNTHESIS AND APPLICATION AS LIGANDS IN THE NICKEL-CATALYZED ENANTIOSELECTIVE CONJUGATE ADDITION OF DIETHYLZINC())

Authors
DEVRIES AHM IMBOS R FERINGA BL
Citation
Ahm. Devries et al., (-CAMPHOR-DERIVED TRIDENTATE AND TETRADENTATE AMINO-ALCOHOLS - SYNTHESIS AND APPLICATION AS LIGANDS IN THE NICKEL-CATALYZED ENANTIOSELECTIVE CONJUGATE ADDITION OF DIETHYLZINC()), Tetrahedron : asymmetry, 8(9), 1997, pp. 1467-1473
Citations number
33
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
9
Year of publication
1997
Pages
1467 - 1473
Database
ISI
SICI code
0957-4166(1997)8:9<1467:(TATA->2.0.ZU;2-A
Abstract
Several novel tri- and tetradentate amino alcohol ligands, all derived from (+)-camphor, have been synthesized by using specific N-alkylatio n procedures. The amino alcohols were employed as chiral ligands in th e nickel catalyzed conjugate additions of diethylzine to chalcone and cyclohexenone as model substrates. For the acyclic enone enantioselect ivities up to 83% were achieved. (C) 1997 Elsevier Science Ltd.