ANTIVIRAL ACTIVITY OF GALANGIN ISOLATED FROM THE AERIAL PARTS OF HELICHRYSUM AUREONITENS

Authors
MEYER JJM AFOLAYAN AJ TAYLOR MB ERASMUS D
Citation
Jjm. Meyer et al., ANTIVIRAL ACTIVITY OF GALANGIN ISOLATED FROM THE AERIAL PARTS OF HELICHRYSUM AUREONITENS, Journal of ethnopharmacology, 56(2), 1997, pp. 165-169
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Journal of ethnopharmacology → ACNP
ISSN journal
03788741
Volume
56
Issue
2
Year of publication
1997
Pages
165 - 169
Database
ISI
SICI code
0378-8741(1997)56:2<165:AAOGIF>2.0.ZU;2-Y
Abstract
The in vitro antiviral activity of galangin (3,5,7-trihydroxyflavone), the major antimicrobial compound isolated from the shoots of Helichry sum aureonitens, was investigated against herpes simplex virus type 1 (HSV-1), coxsackie B virus type 1 (Cox B1), adenovirus type 31 (Ad31) and reovirus. At concentrations ranging from 12-47 mu g/ml galangin sh owed significant antiviral activity against HSV-1 and CoxB1, limited a ctivity against reovirus, and no antiviral activity against Ad31. (C) 1997 Elsevier Science Ireland Ltd.