FURTHER OBSERVATIONS OF TRUE MOSAIC TRISOMY-17 ASCERTAINED IN AMNIOTIC-FLUID CELL-CULTURES

Authors
DJALALI M BARBI G MUELLERNAVIA J SCHNEIDER M TETTENBORN U TRAUTMANN U ULMER R WOLF M VOGEL W
Citation
M. Djalali et al., FURTHER OBSERVATIONS OF TRUE MOSAIC TRISOMY-17 ASCERTAINED IN AMNIOTIC-FLUID CELL-CULTURES, Prenatal diagnosis, 18(11), 1998, pp. 1191-1194
Citations number
16
Categorie Soggetti
Genetics & Heredity","Obsetric & Gynecology
Journal title
Prenatal diagnosis → ACNP
ISSN journal
01973851
Volume
18
Issue
11
Year of publication
1998
Pages
1191 - 1194
Database
ISI
SICI code
0197-3851(1998)18:11<1191:FOOTMT>2.0.ZU;2-Q
Abstract
Three new cases of true mosaic trisomy 17 (MT17) were diagnosed in amn iotic fluid cells. Postnatal chromosome analysis from lymphocytes did not confirm the trisomic cell line, and follow-up studies showed norma l psyche-motor development of the children, in one case up to the age of 41/2 years. We suggest that there are similarities between MT17 and MT20, in which the majority of pregnancies result in deliveries of he althy babies. (C) 1998 John Wiley & Sons, Ltd.