M. Djalali et al., FURTHER OBSERVATIONS OF TRUE MOSAIC TRISOMY-17 ASCERTAINED IN AMNIOTIC-FLUID CELL-CULTURES, Prenatal diagnosis, 18(11), 1998, pp. 1191-1194
Three new cases of true mosaic trisomy 17 (MT17) were diagnosed in amn
iotic fluid cells. Postnatal chromosome analysis from lymphocytes did
not confirm the trisomic cell line, and follow-up studies showed norma
l psyche-motor development of the children, in one case up to the age
of 41/2 years. We suggest that there are similarities between MT17 and
MT20, in which the majority of pregnancies result in deliveries of he
althy babies. (C) 1998 John Wiley & Sons, Ltd.