HALOACETYLATED ENOL ETHERS .8. REACTION OF BETA-ALKOXYVINYL TRIHALOMETHYL KETONES WITH GUANIDINE-HYDROCHLORIDE - SYNTHESIS OF 4-TRIHALOMETHYL-2-AMINOPYRIMIDINES
N. Zanatta et al., HALOACETYLATED ENOL ETHERS .8. REACTION OF BETA-ALKOXYVINYL TRIHALOMETHYL KETONES WITH GUANIDINE-HYDROCHLORIDE - SYNTHESIS OF 4-TRIHALOMETHYL-2-AMINOPYRIMIDINES, Journal of heterocyclic chemistry, 34(2), 1997, pp. 509-513
In this work the results of the reaction of beta-alkoxyvinyl trihalome
thyl ketones 1, 2a-e, with guanidine hydrochloride are reported. Depen
ding on the ketone 1 or 2 and the conditions under which the reactions
were carried our 4-trihalomethyl-2-amino pyrimidines, beta-alkoxyviny
l carboxylic acids, or beta-acetal carboxylic esters were obtained.