CLOTIAPINE - AN OLD NEUROLEPTIC WITH POSSIBLE CLOZAPINE-LIKE PROPERTIES

Citation
P. Lokshin et al., CLOTIAPINE - AN OLD NEUROLEPTIC WITH POSSIBLE CLOZAPINE-LIKE PROPERTIES, Progress in neuro-psychopharmacology & biological psychiatry, 22(8), 1998, pp. 1289-1293
Citations number
9
Categorie Soggetti
Neurosciences,"Clinical Neurology","Pharmacology & Pharmacy",Psychiatry
ISSN journal
02785846
Volume
22
Issue
8
Year of publication
1998
Pages
1289 - 1293
Database
ISI
SICI code
0278-5846(1998)22:8<1289:C-AONW>2.0.ZU;2-O
Abstract
1. This chart survey aims to draw attention to a neuroleptic drug whic h is poorly known but may have atypical properties. 2. Forty patients, thirty four of them suffering from chronic schizophrenia resistant to other neuroleptics, were found to be in clotiapine treatment. A clini cal evaluation was made by the treating doctors and medical personnel. 3. More than sixty percent of the patients suffering from chronic sch izophrenia showed significant improvement and more than thirty five pe rcent showed partial improvement, compared with past function on other neuroleptics. 4. Clotiapine may have clozapine-like effects that requ ire controlled study for confirmation.