PURE SEMINOMATOUS METASTATIC TESTICULAR-TUMORS - INDICATION FOR CHEMOTHERAPY

Citation
B. Ceccaldi et al., PURE SEMINOMATOUS METASTATIC TESTICULAR-TUMORS - INDICATION FOR CHEMOTHERAPY, Bulletin du cancer, 85(10), 1998, pp. 887-891
Citations number
36
Categorie Soggetti
Oncology
Journal title
ISSN journal
00074551
Volume
85
Issue
10
Year of publication
1998
Pages
887 - 891
Database
ISI
SICI code
0007-4551(1998)85:10<887:PSMT-I>2.0.ZU;2-I
Abstract
40% of testicular tumours are seminomatous tumours. The law mass tumou rs (LMT) (stages IIA and IIB of the Royal Mardsen Hospital classificat ion) are usually treated by radiotherapy and the high mass tumours (HM T) (stages IIC, III and IV) by chemotherapy. Chemotherapy regimens are platinum-based polychemotherapy. We report 9 cases of seminomatous te sticular tumours (4 LMT and 5 HMT) treated by chemotherapy (BEP modifi ed or CBDCTA-etoposide regimens), three courses, with one supplement c ourse if necessary and surgery if residual masses are more than 3 cm l ong. The rate of complete remission are 100% for LMT and 60% for HMT T his could be an indication to treat in addition with orchidectomy the LMT with chemotherapy and not with radiotherapy (standard-gold) which is more toxic.