TREATMENT OF DYSKERATOSIS-CONGENITA WITH GRANULOCYTE-COLONY-STIMULATING FACTOR AND ERYTHROPOIETIN

Authors
ALTER BP GARDNER RH HALL RE
Citation
Bp. Alter et al., TREATMENT OF DYSKERATOSIS-CONGENITA WITH GRANULOCYTE-COLONY-STIMULATING FACTOR AND ERYTHROPOIETIN, British Journal of Haematology, 97(2), 1997, pp. 309-311
Citations number
12
Categorie Soggetti
Hematology
Journal title
British Journal of Haematology → ACNP
ISSN journal
00071048
Volume
97
Issue
2
Year of publication
1997
Pages
309 - 311
Database
ISI
SICI code
0007-1048(1997)97:2<309:TODWG>2.0.ZU;2-A
Abstract
Aplastic anaemia is both frequent and difficult to manage in patients with dyskeratosis congenita (DC). We recently treated a 23-year-old ma le for a year with granulocyte colony-stimulating factor (G-CSF) and e rythropoietin (Ep), with an excellent neutrophil response, and a trans ient effect on haemoglobin levels. G-CSF alone or combined with other cytokines may provide at least a partial effect in pancytopenic patien ts with DC.