COMPUTER-ASSISTED REACTION SEARCHING DIRECTED TOWARD THE SYNTHESIS OFTARGET MOLECULES

As a result of an enormous increase of accessible reaction databases a nd the introduction of client-server-based database access systems dur ing the past few years, the computer-assisted searching of reaction da tabases for synthesis planning has become an important part of intense efforts to increase the efficiency and productivity in chemical resea rch. This paper will illustrate effective use of the functionality of MDL's RXL Browser and the concept of retrosynthetic analysis in reacti on searching to derive desirable synthesis plans for target molecules.