UNUSUAL AUTOSOMAL RECESSIVE LYMPHATIC ANOMALIES IN 2 UNRELATED AMISH FAMILIES

We report on two two-related Amish families with familial occurrence o f unusual lymphatic anomalies, The first family had two children, a bo y and a girl, with congenital chylothorax both of wham died as a conse quence of this condition (one prenatally and one neonatally), The seco nd family has two brothers with isolated cystic hygroma, Neither famil y has any other individuals affected with ally type of lymphatic anoma ly. Differential diagnosis and presumed autosomal recessive inheritanc e pattern will be discussed, Familial cystic hygroma not associated wi th hydrops fetalis and neonatal death has not been reported previously . (C) 1997 Wiley-Liss, Inc.