G. Nussey et al., EFFECT OF COPPER ON THE HEMATOLOGY AND OSMOREGULATION OF THE MOZAMBIQUE TILAPIA, OREOCHROMIS-MOSSAMBICUS (CICHLIDAE), Comparative biochemistry and physiology. Part C, Pharmacology toxicology & endocrinology, 111(3), 1995, pp. 369-380
The haematology of Oreachromis mossambicus was investigated after shor
t-term (96 hr) exposures to 0.16 mg/l and 0.40 mg/l, respectively, as
well as long-term (4 wk) exposure of 0.40 mg/l copper, at two temperat
ures, After the exposure of two sublethal copper concentrations a phys
iological effect was exerted on O. mossambicus, at both temperatures,
by causing changes in the blood biochemistry such as leucocytosis and
erythrocytopenia. Morphological changes in the gills, as reflected by
the decreases in the plasma sodium, potassium, calcium and chloride co
ncentrations, although not lethal, had a significant effect on the res
piration and osmoregulatory function of the gills. Those morphological
changes can be regarded as primary changes, which will inevitably lea
d to secondary physiological changes as well as responses that could a
ffect various organ systems. Changes can be seen as an initial respons
e to copper (the toxicant) or as an adaptation reaction to retain a no
rmal condition.