SYNTHESIS OF (ALKOXYCARBONYLOXY)METHYL, (ACYLOXY)METHYL AND (OXODIOXOLENYL)METHYL CARBAMATES AS BIOREVERSIBLE PRODRUG MOIETIES FOR AMINES

Authors
LI Z BITHA P LANG SA LIN YI
Citation
Z. Li et al., SYNTHESIS OF (ALKOXYCARBONYLOXY)METHYL, (ACYLOXY)METHYL AND (OXODIOXOLENYL)METHYL CARBAMATES AS BIOREVERSIBLE PRODRUG MOIETIES FOR AMINES, Bioorganic & medicinal chemistry letters, 7(22), 1997, pp. 2909-2912
Citations number
10
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
22
Year of publication
1997
Pages
2909 - 2912
Database
ISI
SICI code
0960-894X(1997)7:22<2909:SO((A(>2.0.ZU;2-8
Abstract
Synthesis of (alkoxycarbonyloxy)methyl carbamates of secondary amines was developed, and it was extended to (acyloxy)methylation of benzylme thylamine and (oxodioxolenyl)methylation of benzylamine, benzylmethyla mine, and L-phenylalanine. (C) 1997 Elsevier Science Ltd.