G. Nussey et al., EFFECT OF COPPER ON THE DIFFERENTIAL WHITE BLOOD-CELL COUNTS OF THE MOZAMBIQUE TILAPIA (OREOCHROMIS-MOSSAMBICUS), Comparative biochemistry and physiology. Part C, Pharmacology toxicology & endocrinology, 111(3), 1995, pp. 381-388
An increase in the number of leucocytes (leucocytosis) is a normal rea
ction of the fish body, against attacks of foreign substances, such as
copper, which can alter the normal physiological function in fish. Si
gnificant increases in the number of lymphocytes (lymphocytosis) and e
osinophils (eosinophilia) combined with significant decreases in monoc
ytes (monocytopenia) and neutrophils (neutropenia), are indicative of
changes (infections) that set in after short-term (96 hr) exposure to
copper. This finding was confirmed by the number of leucocytes of Oreo
chromis mossambicus that increased at both temperatures, to protect th
e body against infections that may have been caused by copper.