ANDROGEN-BEHAVIOR CORRELATIONS IN HYPOGONADAL MEN AND EUGONADAL MEN .1. MOOD AND RESPONSE TO AUDITORY SEXUAL STIMULI

Mood and response to auditory sexual stimuli were assessed in 33 hypog onadal men receiving testosterone (T) replacement therapy, 10 eugonada l men receiving T in a male contraceptive clinical trial, and 19 eugon adal men not administered T. Prior to and after 6 weeks of hormone adm inistration, men completed a mood questionnaire, rated sexual arousal to and sexual enjoyment of auditory sexual stimuli, and performed a di chotic listening task measuring selective attention for sexual stimuli . Mood questionnaire results suggest that T has positive effects on mo od in hypogonadal men when hormone levels are well below the normal ma le range of values, but does not have any effects on mood when hormone levels are within or above the normal range. However, increased sexua l arousal and sexual enjoyment were associated with T administration r egardless of gonadal status. Eugonadal men administered T also increas ed in the bias to attend to sexual stimuli. In contrast, the compariso n group of eugonadal men not administered T showed no mood or sexual b ehavior changes across the two test sessions. These data support a pos itive relationship between T and sexual interest, sexual arousal, and sexual enjoyment in men. (C) 1997 Academic Press.