CORRELATING IMAGING AND HISTOPATHOLOGY OF AN ODONTOGENIC KERATOCYST IN THE NEVOID BASAL-CELL CARCINOMA SYNDROME

We present the correlative diagnostic imaging and histological finding s in a case of multiple odontogenic keratocysts (OKC) associated with the Nevoid Basal Cell Carcinoma Syndrome (NBCC). Whilst CT displayed a spects of bone morphology not visible on the plain films, contrast-enh anced MR provided the essential macropathological detail, including fo cal wall-enhancement and iso-intense intraluminal soft-tissue masses w hich correlated with the histological findings of focal inflammatory u lceration of the cyst lining, orthokeratosis and cell debris. The feat ures identified by these combined imaging techniques are helpful in di stinguishing the OKC from other cysts or neoplastic lesions and can th erefore alter surgical management.