The improved potentiometric pH response of electrodes modified with processible polyaniline. Application to glucose biosensor

Processible polyaniline (PCPAn) modified electrodes are characterized by an advanced potentiometric pH response in comparison to those based on regula r polyaniline. Glassy carbon electrodes modified with PCPAn by dip-coating exhibited a fully reversible potentiometric response of approximately 90 mV pH(-1) over the range pH 3-9. Such significantly higher potentiometric res ponses of PCPAn modified electrodes compared to existing devices is explain ed on the basis of the thermodynamics of polyaniline redox reactions. The p otentiometric biosensor for glucose based on processible polyaniline has be en developed using a non-aqueous enzymology approach for enzyme immobilizat ion. In the model solution, which mimics blood serum, the biosensor was use ful for glucose detection over the concentration range 0.1-30 mM and the ma ximum response value reached was approximate to 80 mV. The advanced potenti ometric response of PCPAn modified electrodes provides their application fo r sensor and biosensor development.