De. Gutfinger et al., Aggressive preoperative use of intraaortic balloon pump in elderly patients undergoing coronary artery bypass grafting, ANN THORAC, 67(3), 1999, pp. 610-613
Citations number
12
Categorie Soggetti
Cardiovascular & Respiratory Systems","Medical Research Diagnosis & Treatment
Background. The use of the intraaortic balloon pump (IABP) in patients unde
rgoing coronary artery bypass grafting has been traditionally associated wi
th a high complication rate and adverse outcomes. However, recent reports s
how that many of these catastrophic outcomes can be avoided by preoperative
ly placing the IABP in high-risk patients. To further validate these report
s, we defined a set of liberal criteria for preoperative IABP insertion and
applied them to a series of elderly patients (70 years or older) undergoin
g isolated coronary artery bypass grafting.
Methods, Two hundred six consecutive patients who underwent isolated corona
ry artery bypass grafting with cardiopulmonary bypass were retrospectively
reviewed. A rapid recovery protocol emphasizing reduced cardiopulmonary byp
ass Lime, an anesthetic protocol for early extubation, perioperative admini
stration of corticosteroids and thyroid hormone, and aggressive diuresis tv
as applied to all patients. Patients who required an urgent operation becau
se of failed percutaneous transluminal coronary angioplasty, a critical lef
t main stenosis (70% or greater), pronounced left ventricular dysfunction (
left ventricular ejection fraction 40% or less), or unstable angina refract
ory to medical therapy or who required an emergency reoperation received pr
eoperative IABP support.
Results. The 30-day mortality rate for the entire group was 4.4%. There wer
e 97 patients (47%) who received a preoperative IABP (group II) in comparis
on with 109 patients (53%) who did not fulfill the preoperative insertion c
riteria (group I). patients in group II had a lower left ventricular ejecti
on fraction (mean, 46% versus 59%, p < 0.001) and a higher incidence of con
gestive heart failure (35% versus 17%, p < 0.01) and acute myocardial infar
ction (37% versus 17%, p < 0.01) than patients in group I. The average post
operative hospital length of stay for patients in group II was slightly lon
ger than for those in group I (9.0 +/- 10.5 versus 6.0 +/- 3.7 days, p < 0.
01). However, there were no statistically significant differences in compli
cation or mortality rates between the two groups. Only 2 patients (2.2%) ha
d complications related to IABP insertion. Lower extremity ischemia occurre
d in both patients, and both were treated successfully with thromboembolect
omy.
Conclusions. Liberal preoperative insertion of the IABP can be performed sa
fely in high-risk elderly patients undergoing coronary artery bypass grafti
ng, with results comparable to those in lower risk patients. (Ann Thorac Su
rg 1994;67:610-3) (C) 1999 by The Society of Thoracic Surgeons.