Morphological findings and value of placental examination at fetal and perinatal autopsy

The purpose of this study was to report on the morphological findings in pl acentae from abortions, stillbirths and perinatal deaths, and to assess the value of the results of the placental examinations. The material included 341 placentae and their matched autopsies. Fifty placentae came from aborti ons induced for medical reasons, 194 from spontaneous abortions, 84 from st illbirths, and 13 from livebirths. Histological slides from all placentae w ere reviewed and the placental diagnoses were related to the autopsy diagno ses. Frequently observed placental lesions were inflammation of the membran es and/or umbilical cord, placental edema, vascular lesions, single umbilic al artery, and degenerative lesions. The placental examination in pregnanci es terminating with fetal or perinatal death was of value in half the cases . Some placental lesions provide us with clues when assessing the cause of fetal death, but such lesions are rare. Two important groups of lesions, ac ute inflammation of the membranes and/or umbilical cord and lesions consist ent with uteroplacental vascular insufficiency, seen mainly as infarction a nd decidual arteriopathy, were observed. Gross examination is informative, though microscopic examination is often necessary.