Background: Because the risks of sudden cardiac death and myocardial infarc
tion are transiently increased during acute bouts of high-intensity activit
y, it is an important question from the public health perspective whether r
egular participation in moderate-intensity activity confers overall protect
ion from sudden cardiac death.
Participants and Methods: We used data from a population-based case-control
study to assess the associations of regular high-intensity and moderate-in
tensity leisure-time physical activity with primary cardiac arrest. Cases w
ere patients with primary cardiac arrest, aged 25 to 74 years, attended by
paramedics between 1988 and 1994 in King County, Washington (n = 333). Cont
rols were randomly identified from the same community (n = 503), matched fo
r age and sex. All case patients and controls were free of prior clinical h
eart disease, major comorbidity, and self-reported poor health. Spouses of
case patients and controls were interviewed to assess participation in 15 h
igh-intensity and 6 moderate-intensity physical activities during the prior
year.
Results: Compared with subjects who performed none of the activities, the o
dds ratio for primary cardiac arrest from matched analyses was 0.34 (95% co
nfidence interval, 0.13-0.89) among subjects who performed only gardening a
ctivities for more than 60 minutes per week; 0.27 (95% confidence interval,
0.11-0.67) among subjects who walked for exercise for more than 60 minutes
per week; and 0.34 (95% confidence interval, 0.16-0.75) among subjects who
engaged in any high-intensity activities, after adjustment for age, smokin
g, education, diabetes, hypertension, and health status.
Conclusions: The results suggest that regular participation in moderate-int
ensity activities, such as walking and gardening, are associated with a red
uced risk of PCA and support current exercise recommendations.