Cytotoxic constituents from the roots of Anthriscus sylvestris

Authors
Lim, YH Leem, MJ Shin, DH Chang, HB Hong, SW Moon, EY Lee, DK Yoon, SJ Woo, WS
Citation
Yh. Lim et al., Cytotoxic constituents from the roots of Anthriscus sylvestris, ARCH PH RES, 22(2), 1999, pp. 208-212
Citations number
11
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARCHIVES OF PHARMACAL RESEARCH
ISSN journal
02536269 → ACNP
Volume
22
Issue
2
Year of publication
1999
Pages
208 - 212
Database
ISI
SICI code
0253-6269(199904)22:2<208:CCFTRO>2.0.ZU;2-N
Abstract
Activity-guided fractionation of the roots of Anthriscus sylvestris resulte d in the isolation and characterization of five cytotoxic compounds, deoxyp odophyllotoxin (1), falcarindiol (2), and angeloyl podophyllotoxin (5) from the hexane soluble fraction and morelensin (3), bursehernin (4) from the c hloroform soluble fraction. tt is the first report of the occurrence of com pound 5 in nature.