Reactions of chloride salts of 7-amino-9-ethylguanine and 1-amino-3-methylbenzimidazoles with lead(IV) acetate: Formation of 8-aza-9-ethylguanine and1-methyl-1H-benzotriazoles

Authors
Kaiya, T Aoyama, S Kohda, K
Citation
T. Kaiya et al., Reactions of chloride salts of 7-amino-9-ethylguanine and 1-amino-3-methylbenzimidazoles with lead(IV) acetate: Formation of 8-aza-9-ethylguanine and1-methyl-1H-benzotriazoles, BIOORG MED, 9(7), 1999, pp. 961-964
Citations number
35
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
9
Issue
7
Year of publication
1999
Pages
961 - 964
Database
ISI
SICI code
0960-894X(19990405)9:7<961:ROCSO7>2.0.ZU;2-5
Abstract
Reaction of 7-amino-9-ethylguaninium chloride with lead(IV) acetate (LTA) i n MeOH yielded 8-aza-9-ethylguanine. Similarly, the reaction of 1-amino-3-m ethybenzimidazolium chloride or its substituted derivatives (6-methyl, 5,6- dimethyl and 5-nitro) with LTA gave the corresponding 1-methyl-1H-benzotria zole (or 1-methyl-2-azabenzimidazole) derivatives along with N-methylforman ilide derivatives. (C) 1999 Elsevier Science Ltd. All rights reserved.