DIASTEREOSELECTIVE ALPHA-IODINATION REACTION OF 4-ALKENYLAMIDE HAVINGA BETA-CHIRAL CENTER

Authors
OKADA M KITAGAWA O HANANO T TAGUCHI T
Citation
M. Okada et al., DIASTEREOSELECTIVE ALPHA-IODINATION REACTION OF 4-ALKENYLAMIDE HAVINGA BETA-CHIRAL CENTER, Tetrahedron, 53(20), 1997, pp. 6825-6834
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
20
Year of publication
1997
Pages
6825 - 6834
Database
ISI
SICI code
0040-4020(1997)53:20<6825:DARO4H>2.0.ZU;2-P
Abstract
alpha-Iodination reaction of 4-alkenylamide with a beta-chiral center proceeds with high diastereoselectivity to give syn alpha-iodoalkenami de through the formation of cyclic ketene N,O-acetal and subsequent al pha-iodination from the opposite side of a beta-substituent. (C) 1997 Elsevier Science Ltd.