The dependence of catalytic activities of secondary functional beta-cyclodextrins on cavity structures

Authors
Chen, WH Hayashi, S Tahara, T Nogami, Y Koga, T Yamaguchi, M Fujita, K
Citation
Wh. Chen et al., The dependence of catalytic activities of secondary functional beta-cyclodextrins on cavity structures, CHEM PHARM, 47(4), 1999, pp. 588-589
Citations number
9
Categorie Soggetti
Chemistry & Analysis
Journal title
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN journal
00092363 → ACNP
Volume
47
Issue
4
Year of publication
1999
Pages
588 - 589
Database
ISI
SICI code
0009-2363(199904)47:4<588:TDOCAO>2.0.ZU;2-W
Abstract
Secondary imidazole-appended beta-cyclodextrin 5 with a nondistorted cavity synthesized from a novel intermediate 3-amino-3-deoxy-beta-cyclodextrin ex hibits much greater catalytic activity in the ester hydrolysis than its iso mer 6 with a distorted cavity, indicating that the catalytic activities of secondary functional cyclodextrins are dependent on cavity structures.